12 days in Santiago, Mendoza & Buenos Aires Itinerary

12 days in Santiago, Mendoza & Buenos Aires Itinerary

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Route & dates

12 days in Santiago, Mendoza & Buenos Aires Itinerary

Start: Sao Paulo, Brazil
Fly:  6​h 15​min
1
Santiago, Chile
— 4 nights
bus + Fly:  2​h
2
Mendoza, Argentina
— 3 nights
Fly:  3​h 30​min
3
Buenos Aires, Argentina
— 4 nights
Fly:  6​h 45​min
End: Sao Paulo, Brazil

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get a sense of the local culture at La Chascona and Museo Chileno de Arte Precolombino. You'll explore and learn at Museo de la Memoria y los Derechos Humanos and Museo de Artes Visuales. Make the 19th (Sun) a memorable day with a climbing tour. There's much more to do: take your sightseeing to a higher altitude at San Cristóbal Hill, make a trip to Santa Lucia Hill, admire the striking features of Metropolitan Cathedral (Catedral Metropolitana), and steep yourself in history at Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania.

To find maps, other places to visit, photos, and other tourist information, you can read our Santiago online day trip planner .

Sao Paulo, Brazil to Santiago is an approximately 6.5-hour flight. You can also drive; or take a bus. The time zone difference when traveling from Sao Paulo to Santiago is minus 1 hour. Wrap up your sightseeing on the 20th (Mon) to allow time to travel to Mendoza.

Things to do in Santiago

Outdoors Wildlife Tours
Find places to stay Jan 16 — 20:
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San Cristóbal Hill ©
San Cristóbal Hill
La Chascona ©
La Chascona
Museo Chileno de Arte Precolombino ©

3
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Bodega Matervini and Bodega Cruzat. Bubbles Experience are good opportunities to explore the local culture. Go for a jaunt from Mendoza to Las Heras to see Reserva Natural Villavicencio about 52 minutes away. Dedicate the 23rd (Thu) to wine at some of the top wineries in the area. There's more to do: learn about winemaking at Bodega Roberto Bonfanti and take an in-depth tour of Museo Fundacional.

To find photos, ratings, more things to do, and tourist information, use the Mendoza tour itinerary planning tool .

You can do a combination of bus and flight from Santiago to Mendoza in 2 hours. Alternatively, you can drive; or take a bus. The time zone changes from Chile Time to Argentine Time, which is usually a 1 hour difference. January in Mendoza sees daily highs of 38°C and lows of 23°C at night. Wrap up your sightseeing on the 23rd (Thu) to allow time to travel to Buenos Aires.

Things to do in Mendoza

Wineries Tours Parks

Side Trip

Reserva Natural Villavicencio
Find places to stay Jan 20 — 23:
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Bodega Matervini ©
Bodega Matervini
Bodega Tierras Altas ©
Bodega Tierras Altas
Bodega Cruzat. Bubbles Experience ©
Bodega Cruzat. Bubbles Experience

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Museum-lovers will appreciate Museo de Arte Latinoamericano de Buenos Aires and Museo Nacional De Arte Decorativo. Deepen your sense of the past at sights like Plaza de Mayo and Casa Rosada. The adventure continues: take a stroll through Puerto Madero, appreciate the extensive heritage of San Telmo, admire the masterpieces at Museo Nacional de Bellas Artes, and get a taste of the local shopping with Recoleta.

To see reviews, more things to do, traveler tips, and more tourist information, go to the Buenos Aires road trip tool .

Traveling by flight from Mendoza to Buenos Aires takes 3.5 hours. Alternatively, you can drive; or take a bus. While traveling from Mendoza, expect slightly colder days and about the same nights in Buenos Aires, ranging from highs of 33°C to lows of 24°C. Finish your sightseeing early on the 27th (Mon) to allow enough time to travel back home.

Things to do in Buenos Aires

Historic Sites Neighborhoods Museums
Find places to stay Jan 23 — 27:
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Puerto Madero ©
Puerto Madero
Calle Defensa ©
Calle Defensa
Parque 3 de Febrero ©
Parque 3 de Febrero

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