16 days in Chile, Uyuni & Mendoza Itinerary

16 days in Chile, Uyuni & Mendoza Itinerary

Created using Inspirock South America journey planner

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Fly
1
Santiago, Chile
— 1 night
Fly
2
San Pedro de Atacama, Chile
— 1 night
Drive
3
Uyuni, Bolivia
— 4 nights
Drive
4
San Pedro de Atacama, Chile
— 4 nights
Fly
5
Santiago, Chile
— 1 night
Fly
6
Mendoza, Argentina
— 1 night
Fly
7
Santiago, Chile
— 2 nights
Fly

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Santiago, Chile

— 1 night

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
To find ratings, maps, reviews, and more tourist information, you can read our Santiago trip planning tool.

Fortaleza, Brazil to Santiago is an approximately 11.5-hour flight. You can also drive; or take a bus. Due to the time zone difference, you'll gain 1 hour traveling from Fortaleza to Santiago. You'll set off for San Pedro de Atacama on the 22nd (Sun).

Things to do in Santiago

Tours · Outdoors · Shopping · Nightlife
Find places to stay Aug 21 — 22:

San Pedro de Atacama, Chile

— 1 night
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Start off your visit on the 22nd (Sun): explore the activities along Laguna Cejar, contemplate the waterfront views at Tebinquinche Lake, and then take your sightseeing to a higher altitude at Cordillera de la Sal. Get ready for a full day of sightseeing on the next day: pause for some serene contemplation at Iglesia de San Pedro de Atacama and then browse the eclectic array of goods at Feria Artesanal San Pedro de Atacama.

To find maps, photos, more things to do, and tourist information, go to the San Pedro de Atacama trip builder website.

You can fly from Santiago to San Pedro de Atacama in 4 hours. Alternatively, you can drive; or take a bus. August in San Pedro de Atacama sees daily highs of 26°C and lows of 0°C at night. Wrap up your sightseeing by early afternoon on the 23rd (Mon) to allow time for the car ride to Uyuni.

Things to do in San Pedro de Atacama

Nature · Parks · Historic Sites · Shopping
Find places to stay Aug 22 — 23:

Uyuni, Bolivia

— 4 nights
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Step out of Uyuni to go to Potosi and see Pueblo Pulacayo, which is approximately 40 minutes away. And it doesn't end there: explore the striking landscape at Salar de Uyuni, examine the collection at Museo de la Llama y la Sal, step off the mainland to explore Isla Incahuasi, and contemplate the geological forces at Tunupa Volcano.

To see reviews, more things to do, photos, and more tourist information, read our Uyuni trip planner.

Drive from San Pedro de Atacama to Uyuni in 9.5 hours. Alternatively, you can take a bus. Traveling from San Pedro de Atacama in August, you will find days in Uyuni are much colder (7°C), and nights are somewhat warmer (7°C). On the 27th (Fri), wrap the sightseeing up by early afternoon so you can drive to San Pedro de Atacama.

Things to do in Uyuni

Nature · Parks · Museums · Tours

Side Trips

Find places to stay Aug 23 — 27:

San Pedro de Atacama, Chile

— 4 nights
Enjoy San Pedro de Atacama some more: take in the natural beauty of Geyser del Tatio, explore the striking landscape at Valle De La Luna, don't miss a visit to Mirador de Kari, Piedra del Coyote, and explore the activities along Lagunas Miscanti y Miniques.

To see where to stay, photos, other places to visit, and more tourist information, go to the San Pedro de Atacama trip itinerary planning tool.

Drive from Uyuni to San Pedro de Atacama in 9.5 hours. Alternatively, you can take a bus. Traveling from Uyuni in August, expect nights in San Pedro de Atacama to be slightly colder, around 0°C, while days are warmer, around 26°C. Cap off your sightseeing on the 31st (Tue) early enough to catch the flight to Santiago.

Things to do in San Pedro de Atacama

Nature · Parks

Side Trip

Find places to stay Aug 27 — 31:

Santiago, Chile

— 1 night

City of the Island Hills

On the 31st (Tue), admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana), walk around Cerro Santa Lucia, and then take in panoramic vistas at Sky Costanera.

For maps, other places to visit, more things to do, and other tourist information, read our Santiago trip tool.

Traveling by flight from San Pedro de Atacama to Santiago takes 4 hours. Alternatively, you can drive; or take a bus. Finish your sightseeing early on the 1st (Wed) to allow enough time to fly to Mendoza.

Things to do in Santiago

Parks
Find places to stay Aug 31 — Sep 1:

Mendoza, Argentina

— 1 night
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Kick off your visit on the 1st (Wed): do a tasting at Bodega Renacer, don't miss a visit to Plaza Independencia, then stroll around Parque General San Martin, and finally get great views at Cerro de la Gloria. Keep things going the next day: indulge your senses at some of the top wineries in the area.

To find traveler tips, photos, other places to visit, and other tourist information, read our Mendoza trip itinerary planner.

You can fly from Santiago to Mendoza in 4.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Chile Standard Time (CLT) to Argentina Standard Time (ART), which is usually a 1 hour difference. In September, daytime highs in Mendoza are 25°C, while nighttime lows are 9°C. Wrap up your sightseeing on the 2nd (Thu) to allow time to fly to Santiago.

Things to do in Mendoza

Wineries · Tours · Parks
Find places to stay Sep 1 — 2:

Santiago, Chile

— 2 nights

City of the Island Hills

Kick off your visit on the 3rd (Fri): take a stroll through Barrio Bellavista, then see the interesting displays at La Chascona, and then get a taste of the local shopping with Patio Bellavista. Here are some ideas for day two: browse the different shops at Costanera Center, don't miss a visit to Plaza Camilo Mori, then shop like a local with Plop! Galeria, then go for a walk through Plaza de Armas, and finally browse the eclectic array of goods at Central Market (Mercado Central).

Plan trip to Santiago with our itinerary maker to find out where to go and what to do.

You can fly from Mendoza to Santiago in 4.5 hours. Alternatively, you can drive; or take a bus. You'll gain 1 hour traveling from Mendoza to Santiago due to the time zone difference. Finish your sightseeing early on the 4th (Sat) to allow enough time to fly back home.

Things to do in Santiago

Shopping · Neighborhoods · Museums
Find places to stay Sep 2 — 4:

Chile travel guide

4.3
Landmarks · Parks · Specialty Museums
Land of Poets
Squeezed between the Andes and the Pacific Ocean, geographically diverse Chile is a long, thin stretch of land encompassing some of the world's driest deserts in the north, and some of its largest glacial fields in the south. Though most Chile holidays include some form of adventure in the vast wilderness areas, the country also contains charming cities providing plenty of urban things to do and see. Many tours of Chile include at least a brief visit to the country's lush wine regions, where backyard vineyards compete with sprawling estates producing some of the world's most respected whites and reds.