18 days in Rome, Berlin & Prague Itinerary

18 days in Rome, Berlin & Prague Itinerary

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Route & dates

18 days in Rome, Berlin & Prague Itinerary

Start: Sao Paulo, Brazil
1
Rome, Italy
— 6 nights
2
Berlin, Germany
— 5 nights
3
Prague, Czech Republic
— 3 nights
Fly:  5​h
4
Rome, Italy
— 1 night
End: Sao Paulo, Brazil

6
nights
Rome, Italy

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Get some cultural insight at Palatine Hill and Colosseum. Deepen your sense of the past at sights like Vatican Museums and Roman Forum. Explore the numerous day-trip ideas around Rome: Tivoli (Villa d'Este & Villa Adriana). There's much more to do: don't miss a visit to St. Peter's Basilica, take in the architecture and atmosphere at Church of St. Louis of the French, explore the world behind art at Musei Capitolini, and admire the landmark architecture of Pantheon.

Plan my trip to Rome with suggested itineraries provided by Inspirock.

Sao Paulo, Brazil to Rome is an approximately 15-hour combination of bus and flight. You can also do a combination of bus, flight, and train. Due to the time zone difference, you'll lose 4 hours traveling from Sao Paulo to Rome. In May, plan for daily highs up to 28°C, and evening lows to 17°C. Cap off your sightseeing on the 19th (Sun) early enough to travel to Berlin.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trips

Vatican City, Tivoli
Find places to stay May 13 — 19:
Highlights from your plan
Pantheon ©
Pantheon
Colosseum ©
Colosseum
St. Peter's Basilica ©
St. Peter's Basilica

5
nights
Berlin, Germany

Berlin ©
The country's capital and largest city, Berlin is a diverse urban center boasting a lively nightlife and countless things to do.
Get some cultural insight at Pergamonmuseum and Memorial of the Berlin Wall. Your inner history buff will appreciate Charlottenburg Palace and Mauermuseum - Museum Haus am Checkpoint Charlie. And it doesn't end there: examine the collection at Topography of Terror, admire the architecture and history at THE ROOM - Live Escape Game Berlin, get engrossed in the history at Jewish Museum Berlin, and pause for some photo ops at Brandenburg Gate.

For photos, where to stay, ratings, and tourist information, read our Berlin vacation maker site .

You can fly from Rome to Berlin in 5.5 hours. Other options are to drive; or take a train. Finish up your sightseeing early on the 24th (Fri) so you can go by car to Prague.

Things to do in Berlin

Historic Sites Museums Zoos & Aquariums
Find places to stay May 19 — 24:
Highlights from your plan
THE ROOM - Live Escape Game Berlin ©
Pergamonmuseum ©
Pergamonmuseum
Charlottenburg Palace ©
Charlottenburg Palace

3
nights
Prague, Czech Republic

Prague ©
Prague lures millions of tourists each year with its World Heritage-listed medieval city center--a labyrinth of narrow lanes, bridges, cathedrals, and palaces overlooked by a thousand-year-old castle.
Start off your visit on the 25th (Sat): take in the views from Charles Bridge, take in the spiritual surroundings of St. Vitus Cathedral, then explore the historical opulence of Prague Castle, and finally get lost in a book at Strahov Monastery. Get ready for a full day of sightseeing on the 26th (Sun): contemplate the long history of The Powder Tower, get engrossed in the history at Jewish Museum in Prague, then contemplate in the serene atmosphere at Spanish Synagogue, then don't miss a visit to Old Town Square, and finally take some stellar pictures from Prague Astronomical Clock.

For photos, other places to visit, reviews, and tourist information, you can read our Prague route planning website .

Traveling by car from Berlin to Prague takes 3.5 hours. Alternatively, you can fly; or take a train. In May in Prague, expect temperatures between 20°C during the day and 10°C at night. Wrap up your sightseeing by early afternoon on the 27th (Mon) to allow time for travel to Rome.

Things to do in Prague

Historic Sites Museums Neighborhoods
Find places to stay May 24 — 27:
Highlights from your plan
St. Vitus Cathedral ©
St. Vitus Cathedral
Prague Castle ©
Prague Castle
Old Town Square ©
Old Town Square

1
night
Rome, Italy

Rome ©
Kick off your visit on the 28th (Tue): pause for some serene contemplation at Arcibasilica di San Giovanni in Laterano, take in the spiritual surroundings of Vatican City, and then explore the world behind art at Palazzo Doria Pamphilj.

To see ratings, other places to visit, more things to do, and more tourist information, read Rome vacation planner .

Traveling by flight from Prague to Rome takes 5 hours. Alternatively, you can drive; or take a train. In May, Rome is somewhat warmer than Prague - with highs of 28°C and lows of 17°C. Finish your sightseeing early on the 28th (Tue) to allow enough time to travel back home.

Things to do in Rome

Historic Sites Museums

Side Trip

Vatican City
Find places to stay May 27 — 28:
Highlights from your plan
Vatican City ©
Vatican City
Palazzo Doria Pamphilj ©
Palazzo Doria Pamphilj

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