21 days in Argentina, Chile & Peru Itinerary

21 days in Argentina, Chile & Peru Itinerary

Created using Inspirock South America trip itinerary builder

Make it your trip
Fly
1
Buenos Aires, Argentina
— 3 nights
Fly
2
Mendoza, Argentina
— 3 nights
Fly
3
Santiago, Chile
— 3 nights
Drive
4
Valparaiso, Chile
— 4 nights
Fly
5
Cusco, Peru
— 4 nights
Bus to Ollantaytambo, Train to Machu Picchu
6
Machu Picchu, Peru
— 1 night
Fly

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Buenos Aires, Argentina

— 3 nights

Queen of La Plata

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Do some cultural sightseeing at Puerto Madero and Museo de Arte Latinoamericano de Buenos Aires. Museum-lovers will appreciate Museo Nacional de Bellas Artes and Centro Cultural Borges. There's lots more to do: stroll the grounds of Cemiterio de Recoleta, explore the world behind art at Coleccion de Arte Amalia Lacroze de Fortabat, ponder the world of politics at Casa Rosada, and have fun and explore at Museo de los Ninos.

To see other places to visit, ratings, maps, and tourist information, go to the Buenos Aires tour planning app.

Sao Paulo, Brazil to Buenos Aires is an approximately 5.5-hour flight. You can also drive; or do a combination of bus and ferry. Prepare for a bit cooler weather when traveling from Sao Paulo in May: high temperatures in Buenos Aires hover around 20°C and lows are around 14°C. Finish your sightseeing early on the 14th (Fri) so you can fly to Mendoza.

Things to do in Buenos Aires

Museums · Historic Sites · Neighborhoods · Shopping
Find places to stay May 10 — 14:

Mendoza, Argentina

— 3 nights
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Your cultural itinerary includes sights like Bodega Cruzat. Bubbles Experience and Bodega Budeguer. Change things up with these side-trips from Mendoza: Casa El Enemigo (in Maipu) and Valle de Uco (in Tupungato). There's still lots to do: learn about winemaking at Bodega Roberto Bonfanti, sample the fine beverages at Casa Tapaus Destilados, stroll around Parque General San Martin, and get engrossed in the history at Museo Fundacional.

For maps, other places to visit, and more tourist information, go to the Mendoza driving holiday planner.

Traveling by flight from Buenos Aires to Mendoza takes 3.5 hours. Alternatively, you can drive; or take a bus. Plan for little chillier nights when traveling from Buenos Aires in May since evenings lows in Mendoza dip to 9°C. Wrap up your sightseeing on the 17th (Mon) early enough to fly to Santiago.

Things to do in Mendoza

Wineries · Parks · Museums · Nature

Side Trips

Find places to stay May 14 — 17:

Santiago, Chile

— 3 nights

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Satisfy your inner culture vulture at Museo Chileno de Arte Precolombino and Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania. Let the collections at La Chascona and Museo de la Memoria y los Derechos Humanos capture your imagination. There's much more to do: take in the awesome beauty at San Cristóbal Hill, take a stroll through Chilean National Museum of Fine Arts, learn more about the world around you at National Museum of Natural History, and visit Barrio Bellavista.

To see maps, traveler tips, other places to visit, and more tourist information, go to the Santiago online trip builder.

You can fly from Mendoza to Santiago in 4.5 hours. Other options are to drive; or take a bus. You'll gain 1 hour traveling from Mendoza to Santiago due to the time zone difference. Finish up your sightseeing early on the 20th (Thu) so you can go by car to Valparaiso.

Things to do in Santiago

Museums · Neighborhoods · Parks · Nature
Find places to stay May 17 — 20:

Valparaiso, Chile

— 4 nights

Jewel of the Pacific

Navigating through a maze of colorful streets winding up and down steep hills remains an integral part of any Valparaiso tour.
Get some cultural insight at Casa de Isla Negra and Corporacion Museo de Arqueologia e Historia Francisco Fonck. Take a break from the city and head to Playa de Zapallar and Playa El Pejerrey. You'll find plenty of places to visit near Valparaiso: Matetic Vineyards (in Lagunillas) and La Rambla (in Zapallar). There's much more to do: examine the collection at La Sebastiana, don't miss a visit to Edificio Luis Cousino, tour the pleasant surroundings at Rocas de Santo Domingo, and kick back and relax at Reñaca.

Plan my Valparaiso trip by asking Inspirock to come up with tips and suggestions.

Traveling by car from Santiago to Valparaiso takes 1.5 hours. Alternatively, you can take a bus. In May, daytime highs in Valparaiso are 19°C, while nighttime lows are 11°C. Finish up your sightseeing early on the 24th (Mon) so you can catch the flight to Cusco.

Things to do in Valparaiso

Outdoors · Parks · Beaches · Museums

Side Trips

Find places to stay May 20 — 24:

Cusco, Peru

— 4 nights

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Sacsayhuaman and Salinas de Maras are good opportunities to explore the local culture. You'll explore and learn at Museo de Arte Precolombino and Museo de Vida Monastica - Monasterio de Santa Catalina del Cusco. Step out of Cusco to go to Maras and see Moray, which is approximately 1h 20 min away. There's lots more to do: contemplate the long history of Qorikancha, delve into the distant past at Centro Historico De Cusco, pause for some serene contemplation at Cusco Cathedral, and tour the pleasant surroundings at exploor.

To see maps, where to stay, photos, and tourist information, go to the Cusco trip itinerary builder.

You can fly from Valparaiso to Cusco in 6.5 hours. Alternatively, you can drive; or take a bus. Traveling from Valparaiso to Cusco, you'll gain 1 hour due to the time zone difference. Expect somewhat warmer weather when traveling from Valparaiso in May: highs in Cusco hover around 24°C, while lows dip to 4°C. Cap off your sightseeing on the 28th (Fri) early enough to travel to Machu Picchu.

Things to do in Cusco

Historic Sites · Museums · Parks · Neighborhoods

Side Trip

Find places to stay May 24 — 28:

Machu Picchu, Peru

— 1 night
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 29th (Sat): steep yourself in history at Santuario Historico de Machu Picchu, then pause for some serene contemplation at Iglesia Virgen Del Carmen, and then look for gifts at Mapi Art.

To plan Machu Picchu vacation without wasting time, ask Inspirock to design an itinerary.

Getting from Cusco to Machu Picchu by combination of bus and train takes about 4 hours. Other options: take a train; or drive. Finish up your sightseeing early on the 29th (Sat) so you can catch the flight back home.

Things to do in Machu Picchu

Historic Sites · Shopping
Find places to stay May 28 — 29:

Argentina travel guide

4.4
Landmarks · Bodies of Water · Specialty Museums
Land of Contrasts
Home to the highest and lowest points in South America, diverse Argentina enthralls visitors with its contrasting landscapes and rich cultural heritage. A tour of Argentina reveals a sprawling land of fiercely proud and hardworking gauchos, the legendary cowboys of South America's pampas. A vacation in Argentina also leads you to giant urban centers, filled with modern tourist attractions that include fine restaurants, award-winning museums, and renowned public parks, gardens, and zoos. Away from big cities, Argentina sightseeing combines visits to mighty waterfalls situated inside World Heritage-listed national parks in the north of the country, with excursions to icy glaciers in the south.

Chile travel guide

4.3
Landmarks · Parks · Specialty Museums
Land of Poets
Squeezed between the Andes and the Pacific Ocean, geographically diverse Chile is a long, thin stretch of land encompassing some of the world's driest deserts in the north, and some of its largest glacial fields in the south. Though most Chile holidays include some form of adventure in the vast wilderness areas, the country also contains charming cities providing plenty of urban things to do and see. Many tours of Chile include at least a brief visit to the country's lush wine regions, where backyard vineyards compete with sprawling estates producing some of the world's most respected whites and reds.

Peru travel guide

4.6
Historic Sites · Parks · Landmarks
Land of the Incas
In a country renowned for its pre-Columbian archeological sites, no Peru vacation would be complete without an adrenaline-inducing hike to Machu Picchu, World Heritage-listed symbol of the once-mighty Incan Empire. Aside from visiting these spectacular ruins set against the backdrop of photogenic mountain peaks, most holidays in Peru also include an exploration of the country's pretty cities, boasting well-preserved colonial architecture and a slew of modern buildings housing fine museums, galleries, shops, and restaurants. Ideal for active vacationers, Peru trips are also tailor-made for gourmands, as the country's eclectic cuisine blends tasty influences from Africa, Asia, and Europe.