21 days in South America Itinerary

21 days in South America Itinerary

Created using Inspirock South America holiday planner

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Route & dates

21 days in South America Itinerary

Start: Brasilia, Brazil
Fly + Drive:  26​h
1
Machu Picchu, Peru
— 4 nights
Drive + Fly:  20​h 30​min
2
Santiago, Chile
— 2 nights
Fly:  5​h 30​min
3
Montevideo, Uruguay
— 5 nights
4
Buenos Aires, Argentina
— 6 nights
Fly:  6​h 30​min
End: Brasilia, Brazil

4
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Explore hidden gems such as Intipuncu and Qosqo Ayllu. Get a sense of the local culture at Sacred Valley of the Incas and Winay Wayna. Explore the numerous day-trip ideas around Machu Picchu: Moray (in Maras) and Ruinas de Choquequirao (in Cachora). Next up on the itinerary: delve into the distant past at Santuario Historico de Machu Picchu, pause for some serene contemplation at Iglesia Virgen Del Carmen, stop by Mapi Art, and contemplate the long history of Choquequirao Archeological Park.

To find traveler tips and tourist information, read Machu Picchu trip maker site .

Brasilia, Brazil to Machu Picchu is an approximately 26-hour combination of flight and car. You can also drive; or take a bus. Traveling from Brasilia to Machu Picchu, you'll gain 2 hours due to the time zone difference. Wrap up your sightseeing on the 7th (Fri) early enough to travel to Santiago.

Things to do in Machu Picchu

Historic Sites Shopping

Side Trips

Sacred Valley of the Incas, Choquequirao Archeological Park, Qosqo Ayllu, Moray, Ruinas de Choquequirao
Find places to stay Aug 3 — 7:
Highlights from your plan
Santuario Historico de Machu Picchu ©
Intipuncu ©
Intipuncu
Moray ©
Moray

2
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Start off your visit on the 8th (Sat): take in the exciting artwork at E.N.D. Espacio Nacional de Diseno and then browse the exhibits of Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania. Here are some ideas for day two: explore the world behind art at Museo Chileno de Arte Precolombino, then examine the collection at La Chascona, and then get engrossed in the history at Museo de la Memoria y los Derechos Humanos.

To find where to stay, reviews, traveler tips, and tourist information, read our Santiago day trip planning website .

Getting from Machu Picchu to Santiago by combination of car and flight takes about 20.5 hours. Other options: drive; or do a combination of train and bus. The time zone difference moving from Peru Time to Chile Time is 1 hour. Wrap up your sightseeing on the 10th (Mon) to allow time to travel to Montevideo.

Things to do in Santiago

Museums Wineries Shopping

Side Trips

Vina Santa Rita, Vina Undurraga
Find places to stay Aug 8 — 10:
Highlights from your plan
Museo Chileno de Arte Precolombino ©
Vina Santa Rita ©
Vina Santa Rita
Vina Undurraga ©
Vina Undurraga

5
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
1972 Museum and Museo Taller de Casapueblo are good opportunities to explore the local culture. Museo de Replicas en Miniaturas and El 30 Cafe will appeal to museum buffs. Explore Montevideo's surroundings by going to El Aguila (in Atlantida), Piriapolis (Playa Hermosa & Playa Punta Colorada) and Punta Ballena (Playa Solanas & Playa Punta Ballena). The adventure continues: kick back and relax at Playa Portezuelo, explore the world behind art at Museo Nacional de Artes Visuales, tour the pleasant surroundings at Playa Chihuahua, and admire all the interesting features of Finca del Rocio.

To find ratings, maps, and more tourist information, go to the Montevideo trip itinerary builder website .

You can fly from Santiago to Montevideo in 5.5 hours. Alternatively, you can do a combination of flight and bus; or drive. You'll lose 1 hour traveling from Santiago to Montevideo due to the time zone difference. In August, plan for daily highs up to 20°C, and evening lows to 9°C. Finish your sightseeing early on the 16th (Sun) to allow enough time to ride a ferry to Buenos Aires.

Things to do in Montevideo

Outdoors Beaches Parks

Side Trips

Maldonado, Piriapolis, El Aguila, Museo de Replicas en Miniaturas
Find places to stay Aug 10 — 16:
Highlights from your plan
Catedral de Montevideo ©
Catedral de Montevideo
1972 Museum ©
1972 Museum
Museo Torres Garcia ©
Museo Torres Garcia

6
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Shop till you drop at Puerto Madero and Galerias Pacifico. Your inner history buff will appreciate Catedral de la Plata and Catedral Metropolitana. Take a break from Buenos Aires with a short trip to Museo de La Plata in La Plata, about 1h 15 min away. And it doesn't end there: explore the world behind art at Museo Nacional de Bellas Artes, take a stroll through Palermo, get to know the fascinating history of San Telmo, and make a trip to Plaza de Mayo.

To see photos, other places to visit, where to stay, and tourist information, read our Buenos Aires trip itinerary planner .

You can ride a ferry from Montevideo to Buenos Aires in 2.5 hours. Alternatively, you can fly; or take a bus. In August in Buenos Aires, expect temperatures between 20°C during the day and 12°C at night. Wrap up your sightseeing on the 22nd (Sat) early enough to travel back home.

Things to do in Buenos Aires

Neighborhoods Historic Sites Museums

Side Trip

La Plata
Find places to stay Aug 16 — 22:
Highlights from your plan
Puerto Madero ©
Puerto Madero
Palermo Soho ©
Palermo Soho
Catedral de la Plata ©
Catedral de la Plata

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