22 days in Northwest Italy Itinerary

22 days in Northwest Italy Itinerary

Created using Inspirock Northwest Italy holiday builder

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Route & dates

22 days in Northwest Italy Itinerary

Start: Sao Jose Do Rio Preto
Fly:  23​h 30​min
1
Rome
— 4 nights
2
Assisi
— 3 nights
Drive:  1​h 45​min
3
Siena
— 3 nights
bus:  1​h 15​min
4
Florence
— 3 nights
5
Verona
— 2 nights
bus:  1​h 30​min
6
Venice
— 4 nights
Fly:  25​h
End: Sao Jose Do Rio Preto

4
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, museums, classes, and shopping. Your plan includes some of its best attractions: delve into the distant past at Colosseum, get to know the fascinating history of Piazza Navona, contemplate the long history of Roman Forum, and explore the world behind art at Galleria Borghese.

To find maps, ratings, other places to visit, and more tourist information, you can read our Rome journey builder app .

Sao Jose Do Rio Preto, Brazil to Rome is an approximately 23.5-hour flight. Due to the time zone difference, you'll lose 4 hours traveling from Sao Jose Do Rio Preto to Rome. Traveling from Sao Jose Do Rio Preto in September, expect Rome to be a bit cooler, temps between 32°C and 18°C. Wrap up your sightseeing on the 22nd (Sun) to allow time to drive to Assisi.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trip

Vatican City
Find places to stay Sep 18 — 22:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
St. Peter's Basilica ©
St. Peter's Basilica

3
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Explore Assisi's surroundings by going to Montefalco (Wild Foods Italy & Montioni Frantoio e Cantina) and Castello Monte Vibiano Vecchio (in Mercatello). The adventure continues: take in the architecture and atmosphere at Basilica Papale e Sacro Convento di San Francesco d'Assisi, walk around Mount Subasio, examine the collection at Museo della Porziuncola, and do a tasting at Tili Vini Societa Agricola.

To find photos, reviews, where to stay, and other tourist information, you can read our Assisi day trip website .

Drive from Rome to Assisi in 2.5 hours. Alternatively, you can take a train; or take a bus. In September, daily temperatures in Assisi can reach 30°C, while at night they dip to 16°C. Finish up your sightseeing early on the 25th (Wed) so you can go by car to Siena.

Things to do in Assisi

Historic Sites Wineries Parks

Side Trips

Montefalco, Castello Monte Vibiano Vecchio
Find places to stay Sep 22 — 25:
Highlights from your plan
Museo della Porziuncola ©
Museo della Porziuncola
Eremo delle Carceri ©
Eremo delle Carceri

3
nights
Siena

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
You'll find plenty of places to visit near Siena: Guardastelle Vineyard (in San Gimignano) and Ciacci Piccolomini d'Aragona (in Castelnuovo dell'Abate). There's lots more to do: savor the flavors at Food & Drink, browse the collection at Biblioteca Piccolomini, admire the masterpieces at Museo dell'Opera Metropolitana, and don't miss a visit to Piazza del Campo.

To find photos, other places to visit, ratings, and tourist information, read Siena road trip app .

You can drive from Assisi to Siena in 2 hours. Other options are to take a bus; or take a train. In September, daytime highs in Siena are 32°C, while nighttime lows are 19°C. Wrap up your sightseeing on the 28th (Sat) to allow time to take a bus to Florence.

Things to do in Siena

Wineries Tours Historic Sites

Side Trips

Guardastelle Vineyard, Ciacci Piccolomini d'Aragona
Find places to stay Sep 25 — 28:
Highlights from your plan
Wine Tours & Tastings
Piazza del Campo ©
Piazza del Campo
Duomo di Siena ©
Duomo di Siena

3
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Take a break from Florence with a short trip to Leaning Tower of Pisa in Pisa, about 1h 10 min away. The adventure continues: admire the masterpieces at Gallerie Degli Uffizi, take some stellar pictures from Piazzale Michelangelo, get engrossed in the history at Basilica di Santa Croce, and snap pictures at Ponte Vecchio.

For photos, reviews, ratings, and tourist information, read our Florence day trip app .

You can take a bus from Siena to Florence in 1.5 hours. Other options are to drive; or take a train. Expect a daytime high around 30°C in September, and nighttime lows around 17°C. Cap off your sightseeing on the 1st (Tue) early enough to catch the train to Verona.

Things to do in Florence

Museums Historic Sites

Side Trip

Leaning Tower of Pisa
Find places to stay Sep 28 — Oct 1:
Highlights from your plan
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

2
nights
Verona

Verona ©
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
Start off your visit on the 2nd (Wed): snap pictures at Ponte Scaligero (Ponte di Castelvecchio), contemplate in the serene atmosphere at Basilica di San Zeno Maggiore, explore the historical opulence of Museo di Castelvecchio, make a trip to Piazza Bra, then admire the striking features of Casa di Giulietta, and finally experience the emotional art of opera at Arena di Verona. Get ready for a full day of sightseeing on the next day: stop by Diletta Sicilia, enjoy breathtaking views from Torre dei Lamberti, take a stroll through Piazza delle Erbe, then wander the streets of Quinzano, and finally head outdoors with King Rock arrampicata.

For more things to do, ratings, traveler tips, and more tourist information, read our Verona road trip planner .

Traveling by train from Florence to Verona takes 2 hours. Alternatively, you can drive; or take a bus. While traveling from Florence, expect slightly colder days and about the same nights in Verona, ranging from highs of 22°C to lows of 11°C. Wrap up your sightseeing on the 3rd (Thu) early enough to take a bus to Venice.

Things to do in Verona

Historic Sites Outdoors Neighborhoods
Find places to stay Oct 1 — 3:
Highlights from your plan
Arena di Verona ©
Arena di Verona
Piazza delle Erbe ©
Piazza delle Erbe
Basilica di San Zeno Maggiore ©
Basilica di San Zeno Maggiore

4
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Venture out of the city with trips to Padua (Scrovegni Chapel & Basilica di Sant’Antonio). There's still lots to do: contemplate the waterfront views at Canal Grande, take in the views from Ponte di Rialto, appreciate the extensive heritage of Piazza San Marco, and contemplate the long history of Ponte dei Sospiri.

To see maps, reviews, more things to do, and tourist information, refer to the Venice itinerary planner.

Getting from Verona to Venice by bus takes about 1.5 hours. Other options: drive; or take a shuttle. In October, daily temperatures in Venice can reach 22°C, while at night they dip to 12°C. Finish up your sightseeing early on the 7th (Mon) so you can travel back home.

Things to do in Venice

Historic Sites Museums Nature

Side Trip

Padua
Find places to stay Oct 3 — 7:
Highlights from your plan
Canal Grande ©
Canal Grande
Piazza San Marco ©
Piazza San Marco
Basilica di San Marco
Basilica di San Marco

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