24 days in South America Itinerary

24 days in South America Itinerary

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Route & dates

24 days in South America Itinerary

Start: Frankfurt, Germany
Fly:  15​h 15​min
1
Sao Paulo, Brazil
— 4 nights
Fly:  3​h 30​min
2
Foz do Iguacu, Brazil
— 1 night
Drive:  4​h 45​min
3
Asuncion, Paraguay
— 3 nights
Fly:  2​h 30​min
4
Montevideo, Uruguay
— 3 nights
ferry:  2​h 45​min
5
Buenos Aires, Argentina
— 4 nights
Fly:  16​h 30​min
6
Santiago, Chile
— 4 nights
Fly:  6​h 45​min
7
Sao Paulo, Brazil
— 1 night
Fly:  15​h 15​min
End: Frankfurt, Germany

4
nights
Sao Paulo, Brazil

Sao Paulo ©
Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
Get in touch with nature at Fazenda Ipanema and Praia Guarau. Step off the beaten path and head to Mosteiro De Sao Bento and Santuario Sao Francisco. Go for a jaunt from Sao Paulo to Campinas to see Nossa Senhora da Conceicao Metropolitan Cathedral about 1h 50 min away. There's lots more to do: explore the world behind art at Pinacoteca do Estado de Sao Paulo, contemplate in the serene atmosphere at Catedral Evangelica de Sao Paulo, view the masterpieces at Centro Cultural Banco do Brasil, and pause for some serene contemplation at Catedral da Se de Sao Paulo.

To see other places to visit, ratings, traveler tips, and tourist information, refer to the Sao Paulo day trip app .

Frankfurt, Germany to Sao Paulo is an approximately 15.5-hour flight. You can also do a combination of flight and bus. Due to the time zone difference, you'll gain 4 hours traveling from Frankfurt to Sao Paulo. Plan for somewhat warmer temperatures traveling from Frankfurt in September, with highs in Sao Paulo at 30°C and lows at 18°C. Cap off your sightseeing on the 27th (Fri) early enough to travel to Foz do Iguacu.

Things to do in Sao Paulo

Museums Historic Sites Parks

Side Trips

Praia Guarau, Nossa Senhora da Conceicao Metropolitan Cathedral, Fazenda Ipanema
Find places to stay Sep 23 — 27:
Highlights from your plan
Mosteiro De Sao Bento ©
Mosteiro De Sao Bento
Praia Guarau ©
Praia Guarau

1
night
Foz do Iguacu, Brazil

Foz do Iguacu ©
A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.
On the 27th (Fri), look for gifts at Orquidario Vale Das Orquideas, then contemplate in the serene atmosphere at Buddhist Temple, and then look for all kinds of wild species at Bela Vista Ecological Refuge.

To see ratings, other places to visit, reviews, and other tourist information, read our Foz do Iguacu driving holiday planner .

Traveling by flight from Sao Paulo to Foz do Iguacu takes 3.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Expect a daytime high around 32°C in September, and nighttime lows around 17°C. Finish your sightseeing early on the 28th (Sat) to allow enough time to travel to Asuncion.

Things to do in Foz do Iguacu

Wildlife Parks Historic Sites
Find places to stay Sep 27 — 28:
Highlights from your plan
Bela Vista Biological Refuge ©
Bela Vista Biological Refuge
Buddhist Temple ©
Buddhist Temple
Orquidario Vale Das Orquideas ©
Orquidario Vale Das Orquideas

3
nights
Asuncion, Paraguay

Asuncion ©
Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
Get some historical perspective at Casa de la Independencia and Catedral de Nuestra Senora de la Asuncion. Catedral Virgen de Caacupe and El Cantaro, Almacen de Arte are good opportunities to explore the local culture. Next up on the itinerary: get engrossed in the history at Gran Hotel del Paraguay, admire the striking features of Panteon Nacional de los Heroes, head outdoors with Parque de la Salud, and ponder the world of politics at Palacio de López.

Plan a trip to Asuncion easily and quickly by telling Inspirock to suggest an itinerary.

You can do a combination of car and flight from Foz do Iguacu to Asuncion in 1.5 hours. Other options are to do a combination of bus and taxi; or drive. The time zone changes from Brasilia Time (BRT) to Paraguay Time (PYT), which is usually a -1 hour difference. In September, plan for daily highs up to 33°C, and evening lows to 19°C. Finish up your sightseeing early on the 1st (Tue) so you can travel to Montevideo.

Things to do in Asuncion

Outdoors Historic Sites Parks

Side Trip

Catedral Virgen de Caacupe
Find places to stay Sep 28 — Oct 1:
Highlights from your plan
Parque Nu Guasu ©
Parque Nu Guasu
Catedral Virgen de Caacupe ©
Catedral Virgen de Caacupe
Casa de la Independencia ©
Casa de la Independencia

3
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
You'll explore the less-touristy side of things at Catedral Matriz and Iglesia de las Carmelitas. Your cultural itinerary includes sights like Pocitos and Bouza Bodega Boutique. Change things up with a short trip to Pizzorno Family Estates in Canelones (about 42 minutes away). There's still lots to do: take a stroll through Ciudad Vieja, admire the masterpieces at Museo Municipal de Bellas Artes Juan Manuel Blanes, get a sense of history and politics at Estevez Palace, and step into the grandiose world of Pittamiglio"s Castle.

To see more things to do, maps, reviews, and more tourist information, read our Montevideo trip planning website .

Traveling by flight from Asuncion to Montevideo takes 2.5 hours. Alternatively, you can drive; or do a combination of taxi, bus, and ferry. Due to the time zone difference, you'll lose 1 hour traveling from Asuncion to Montevideo. Traveling from Asuncion in October, expect Montevideo to be slightly colder, temps between 23°C and 13°C. Finish your sightseeing early on the 4th (Fri) so you can ride a ferry to Buenos Aires.

Things to do in Montevideo

Wineries Shopping Neighborhoods

Side Trip

Pizzorno Family Estates
Find places to stay Oct 1 — 4:
Highlights from your plan
Pizzorno Family Estates ©
Pizzorno Family Estates
Catedral de Montevideo ©
Catedral de Montevideo
Iglesia de las Carmelitas ©
Iglesia de las Carmelitas

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Get some cultural insight at Puerto Madero and Plaza de Mayo. Eschew the tourist crowds and head to Basilica de Lujan and Basilica del Santisimo Sacramento. Explore the numerous day-trip ideas around Buenos Aires: Museo de La Plata (in La Plata), Reserva Natural Urbana (in Castelar) and Museos & Cripta Basilica Nuestra Senora De Lujan (in Lujan). There's still lots to do: take in nature's colorful creations at Parque 3 de Febrero, wander the streets of Recoleta, take in the spiritual surroundings of Basilica de Nuestra Senora Del Pilar, and appreciate the extensive heritage of San Telmo.

To see other places to visit, more things to do, ratings, and other tourist information, go to the Buenos Aires road trip site .

You can ride a ferry from Montevideo to Buenos Aires in 2.5 hours. Alternatively, you can fly; or take a bus. In October, plan for daily highs up to 24°C, and evening lows to 17°C. Finish up your sightseeing early on the 8th (Tue) so you can travel to Santiago.

Things to do in Buenos Aires

Historic Sites Neighborhoods Museums

Side Trips

Lujan, Reserva Natural Urbana, Museo de La Plata
Find places to stay Oct 4 — 8:
Highlights from your plan
Puerto Madero ©
Puerto Madero
Basilica de Lujan ©
Basilica de Lujan
Basilica del Santisimo Sacramento ©

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get some cultural insight at La Chascona and Concha y Toro. Popular historic sites such as Sewell and Castillo Hidalgo are in your itinerary. Change things up with these side-trips from Santiago: Museo de la Gran Mineria de Cobre (in Machali), Hacienda Picarquin (in Rancagua) and Vina Undurraga (in Talagante). Next up on the itinerary: take your sightseeing to a higher altitude at San Cristóbal Hill, contemplate in the serene atmosphere at Templo Baha'i, and steep yourself in history at Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania.

To see reviews, ratings, photos, and tourist information, read our Santiago route builder tool .

You can fly from Buenos Aires to Santiago in 5.5 hours. Other options are to drive; or take a bus. Traveling from Buenos Aires to Santiago, you'll gain 1 hour due to the time zone difference. Finish up your sightseeing early on the 13th (Sun) so you can travel to Sao Paulo.

Things to do in Santiago

Parks Historic Sites Wineries

Side Trips

Machali, Hacienda Picarquin, Concha y Toro, Vina Undurraga
Find places to stay Oct 9 — 13:
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Vina Undurraga ©
Vina Undurraga
Templo Baha'i ©
Templo Baha'i

1
night
Sao Paulo, Brazil

Sao Paulo ©
On the 13th (Sun), take a stroll through Paulista Avenue, then see the interesting displays at Football Museum, and then take in the spiritual surroundings of Paróquia Nossa Senhora do Brasil.

To find other places to visit, reviews, ratings, and tourist information, go to the Sao Paulo road trip app .

Traveling by flight from Santiago to Sao Paulo takes 7 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Santiago to Sao Paulo is 1 hour. On the 14th (Mon), you'll have the morning to explore before heading back home.

Things to do in Sao Paulo

Historic Sites Shopping Neighborhoods
Find places to stay Oct 13 — 14:
Highlights from your plan
Paróquia Nossa Senhora do Brasil ©
Paróquia Nossa Senhora do Brasil
Paulista Avenue ©
Paulista Avenue
Igreja Chagas do Serafico Pai Francisco ©

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