28 days in South America Itinerary

Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.

To find traveler tips, where to stay, ratings, and more tourist information, read Rio de Janeiro road trip planning site.

London, UK to Rio de Janeiro is an approximately 15.5-hour flight. The time zone changes from Greenwich Mean Time (GMT) to Brasilia Standard Time (BRT), which is usually a -3 hour difference. Prepare for much hotter weather when traveling from London in November: high temperatures in Rio de Janeiro hover around 33°C and lows are around 25°C. On the 1st (Tue), you're off to Sao Paulo.

Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.

Plan a trip to Sao Paulo easily and quickly by telling Inspirock to suggest an itinerary.

Getting from Rio de Janeiro to Sao Paulo by flight takes about 3.5 hours. Other options: drive; or take a bus. Expect a bit cooler temperatures when traveling from Rio de Janeiro in December; daily highs in Sao Paulo reach 32°C and lows reach 22°C. On the 3rd (Thu), you're off to Foz do Iguacu.

A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.

For maps, where to stay, other places to visit, and tourist information, use the Foz do Iguacu online trip builder.

Fly from Sao Paulo to Foz do Iguacu in 4 hours. Alternatively, you can fly; or drive; or take a bus. In December, daily temperatures in Foz do Iguacu can reach 36°C, while at night they dip to 24°C. Finish your sightseeing early on the 5th (Sat) so you can travel to La Paz.

Take a moment to catch your breath as you commence your holiday in La Paz.

To see reviews, other places to visit, photos, and other tourist information, you can read our La Paz route planner.

Fly from Foz do Iguacu to La Paz in 11.5 hours. Alternatively, you can fly; or drive; or take a bus. Traveling from Foz do Iguacu to La Paz, you'll gain 1 hour due to the time zone difference. Expect much colder temperatures when traveling from Foz do Iguacu in December; daily highs in La Paz reach 18°C and lows reach 3°C. On the 8th (Tue), you're off to Uyuni.

Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.

For photos, where to stay, and other tourist information, you can read our Uyuni online trip maker.

Getting from La Paz to Uyuni by bus takes about 9 hours. Other options: fly; or drive; or take a bus. Traveling from La Paz in December, expect nights in Uyuni to be somewhat warmer, around 13°C, while days are a bit cooler, around 13°C. You will leave for San Pedro de Atacama on the 12th (Sat).

Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.

Inspirock's itinerary builder makes planning a San Pedro de Atacama trip simple and quick.

Traveling by car from Uyuni to San Pedro de Atacama takes 12 hours. Alternatively, you can drive; or take a bus. While traveling from Uyuni, expect warmer days and a bit cooler nights in San Pedro de Atacama, ranging from highs of 29°C to lows of 6°C. You'll have a few hours on the 13th (Sun) to wrap things up before traveling to Santiago.

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.

To find photos, more things to do, maps, and other tourist information, read our Santiago planner.

Traveling by journey from San Pedro de Atacama to Santiago takes 6.5 hours. Alternatively, you can fly; or drive; or take a bus. You'll set off for Valparaiso on the 14th (Mon).

Navigating through a maze of colorful streets winding up and down steep hills remains an integral part of any Valparaiso tour.

To see reviews and tourist information, use the Valparaiso vacation planner.

Traveling by bus from Santiago to Valparaiso takes 1.5 hours. Alternatively, you can drive; or take a bus. In December, daytime highs in Valparaiso are 24°C, while nighttime lows are 15°C. On the 16th (Wed), you're off to Punta Arenas.

An erstwhile hub of the sheep wool industry, Punta Arenas has evolved into a gateway of sorts for hikers, cruise ship passengers, and adventure travelers heading out on the windswept lands of Chile's extreme southern reaches.

To find ratings, more things to do, photos, and more tourist information, you can read our Punta Arenas trip itinerary builder site.

Traveling by flight from Valparaiso to Punta Arenas takes 7.5 hours. Alternatively, you can drive; or take a bus. In December, Punta Arenas is slightly colder than Valparaiso - with highs of 15°C and lows of 6°C. You'll set off for Puerto Natales (Torres del Paine) on the 16th (Wed).

Surrounded by towering mountains, shimmering lakes, and the region's rugged hills, Puerto Natales serves as a bustling jumping-off point for exploring the Torres del Paine National Park.

For other places to visit, more things to do, photos, and other tourist information, read Puerto Natales (Torres del Paine) online trip planner.

You can take a bus from Punta Arenas to Puerto Natales (Torres del Paine) in 3 hours. Alternatively, you can take a bus; or drive. In December, daily temperatures in Puerto Natales (Torres del Paine) can reach 15°C, while at night they dip to 9°C. On the 20th (Sun), you'll have the morning to explore before heading off to Buenos Aires.

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.

To find other places to visit, ratings, more things to do, and more tourist information, use the Buenos Aires trip planner.

Fly from Puerto Natales (Torres del Paine) to Buenos Aires in 10.5 hours. Alternatively, you can do a combination of bus and flight; or drive; or take a bus. You'll lose 1 hour traveling from Puerto Natales (Torres del Paine) to Buenos Aires due to the time zone difference. Plan for much hotter temperatures traveling from Puerto Natales (Torres del Paine) in December, with highs in Buenos Aires at 33°C and lows at 23°C. You will leave for home on the 23rd (Wed).