49 days in South America Itinerary

49 days in South America Itinerary

Created using Inspirock South America vacation planner

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Fly
1
Quito, Ecuador
— 4 nights
+2
Fly to Baltra Island, Fly to San Cristobal, Ferry to Puerto Ayora
2
Puerto Ayora, Ecuador
— 7 nights
+2
Ferry to San Cristobal, Fly to Baltra Island, Fly to Guayaquil
3
Guayaquil, Ecuador
— 3 nights
Fly
4
Lima, Peru
— 5 nights
Fly
5
Machu Picchu, Peru
— 2 nights
Train to Ollantaytambo, Bus to Cusco
6
Cusco, Peru
— 6 nights
Fly
7
La Paz, Bolivia
— 3 nights
Fly
8
Uyuni, Bolivia
— 1 night
Fly
9
Gramado, Brazil
— 4 nights
Fly
10
Sao Paulo, Brazil
— 5 nights
Fly
11
Rio de Janeiro, Brazil
— 6 nights
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4
nights
Quito, Ecuador

Light of America

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
You'll explore and learn at Museo Templo del Sol Pintor Ortega Maila and Centro de Arte Contemporáneo de Quito. Head to Lindberg Galeria/Taller and Olga Fisch Folklorefor plenty of shopping. Spend the 16th (Tue) among the fascinating landscape of Cotopaxi National Park. There's lots more to do: examine the collection at Museo Etnohistorico de Artesanias del Ecuador Mindalae, pause for some serene contemplation at Iglesia y Convento de San Francisco, explore the world behind art at Convento De San Francisco, and admire the landmark architecture of Fundacion Iglesia de la Compania.

For where to stay, reviews, traveler tips, and other tourist information, you can read our Quito online travel route planner.

London, UK to Quito is an approximately 18-hour flight. The time zone changes from Greenwich Mean Time to Ecuador Time, which is usually a -5 hour difference. Expect somewhat warmer evenings in Quito when traveling from London in June, with lows around 17°C. Wrap up your sightseeing on the 17th (Wed) to allow time to travel to Puerto Ayora.

Things to do in Quito

Museums · Wildlife · Parks · Nature

Side Trip

Find places to stay Jun 13 — 17:

7
nights
Puerto Ayora, Ecuador

The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.
Satisfy your inner culture vulture at Galeria Aymara and The Angelique Art Gallery. You'll get in some beach time at Galapagos Beach at Tortuga Bay and Playa de La Estacion. Change things up with a short trip to North Seymour Island in Baltra (about 1h 20 min away). And it doesn't end there: tour the pleasant surroundings at Charles Darwin Research Station, enjoy the sand and surf at Playa de los Perros, see some colorful creatures with a scuba or snorkeling tour, and walk around El Garrapatero.

For where to stay, more things to do, ratings, and tourist information, you can read our Puerto Ayora day trip app.

Getting from Quito to Puerto Ayora by combination of flight and ferry takes about 9.5 hours. Traveling from Quito in June, things will get somewhat warmer in Puerto Ayora: highs are around 33°C and lows about 26°C. Cap off your sightseeing on the 24th (Wed) early enough to travel to Guayaquil.

Things to do in Puerto Ayora

Parks · Outdoors · Beaches · Nature

Side Trips

Find places to stay Jun 17 — 24:

3
nights
Guayaquil, Ecuador

Pearl of the Pacific

Hills dotted with colorful houses and waterfront promenades typify Guayaquil, Ecuador's largest city and commercial center.
Satisfy your inner culture vulture at Guayaquil Historical Park and Museum of Anthropology and Contemporary Art. Let the collections at Presley Norton Museum and Casa Marin capture your imagination. There's much more to do: identify plant and animal life at Wildlife Areas, brush up on your military savvy at Museo en Miniatura Guayaquil en la Historia, visit Las Penas, and wander the streets of Cerro Santa Ana.

To see traveler tips, ratings, other places to visit, and tourist information, use the Guayaquil sightseeing planning website.

You can do a combination of ferry and flight from Puerto Ayora to Guayaquil in 8.5 hours. In June, daytime highs in Guayaquil are 35°C, while nighttime lows are 26°C. Finish up your sightseeing early on the 27th (Sat) so you can travel to Lima.

Things to do in Guayaquil

Wildlife · Museums · Neighborhoods · Parks
Find places to stay Jun 24 — 27:

5
nights
Lima, Peru

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Museum-lovers will get to explore Museo Larco and Galeria Indigo. Get some cultural insight at Museo Convento San Francisco y Catacumbas and Huaca Pucllana. There's much more to do: get engrossed in the history at Museo de la Nacion, admire the masterpieces at Museo Senor De Los Milagros, view the masterpieces at Jade Rivera World, and examine the collection at ChocoMuseo Kennedy.

To find other places to visit, photos, traveler tips, and tourist information, read Lima online trip itinerary maker.

You can fly from Guayaquil to Lima in 5 hours. Other options are to drive; or take a bus. Expect a bit cooler temperatures when traveling from Guayaquil in June; daily highs in Lima reach 24°C and lows reach 20°C. Wrap up your sightseeing on the 2nd (Thu) early enough to travel to Machu Picchu.

Things to do in Lima

Museums · Historic Sites · Shopping · Childrens Museums
Find places to stay Jun 27 — Jul 2:

2
nights
Machu Picchu, Peru

A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Kick off your visit on the 3rd (Fri): steep yourself in history at Santuario Historico de Machu Picchu. Keep things going the next day: explore the ancient world of Winay Wayna.

You can plan Machu Picchu trip in no time by asking Inspirock to help create your itinerary.

Getting from Lima to Machu Picchu by flight takes about 7 hours. Other options: drive; or do a combination of bus and taxi. On the 4th (Sat), wrap the sightseeing up by early afternoon so you can travel to Cusco.

Things to do in Machu Picchu

Historic Sites
Find places to stay Jul 2 — 4:

6
nights
Cusco, Peru

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Museum-lovers will appreciate Museo de Arte Precolombino and Museo y Catacumbas Del Convento San Francisco de Asis Del Cusco. For shopping fun, head to Centro de Textiles Tradicionales del Cusco or Museo Maximo Laura. Explore Cusco's surroundings by going to Qosqo Ayllu (in Ollantaytambo) and Maras (Salinas de Maras & Moray). There's still lots to do: steep yourself in history at Sacsayhuaman, get engrossed in the history at Museo de Vida Monastica - Monasterio de Santa Catalina del Cusco, explore the ancient world of Tipon, and surround yourself with nature on a nature and wildlife tour.

For more things to do, where to stay, traveler tips, and more tourist information, refer to the Cusco trip builder tool.

You can do a combination of train and bus from Machu Picchu to Cusco in 4 hours. Alternatively, you can take a train; or drive. In July, plan for daily highs up to 24°C, and evening lows to 1°C. Wrap up your sightseeing on the 10th (Fri) to allow time to travel to La Paz.

Things to do in Cusco

Historic Sites · Museums · Outdoors · Tours

Side Trips

Find places to stay Jul 4 — 10:

3
nights
La Paz, Bolivia

City that Touches the Sky

Take a moment to catch your breath as you commence your holiday in La Paz.
Get some cultural insight at Tiwanaku and Museo de Textiles Andinos Bolivianos. You'll explore and learn at Museo de Metales Preciosos and National Museum of Ethnography and Folklore. Go for a jaunt from La Paz to Tiahuanaco to see Puma Punku about 1h 10 min away. There's lots more to do: make a trip to Mercado de Las Brujas, look for gifts at Mistura - Manifestacion Creativa, and take in the exciting artwork at Casa Museo Solon.

To find where to stay, maps, traveler tips, and more tourist information, you can read our La Paz holiday maker.

Fly from Cusco to La Paz in 4.5 hours. Alternatively, you can drive; or take a bus. Due to the time zone difference, you'll lose 1 hour traveling from Cusco to La Paz. Prepare for little chillier weather when traveling from Cusco in July: high temperatures in La Paz hover around 17°C and lows are around -4°C. Finish up your sightseeing early on the 13th (Mon) so you can travel to Uyuni.

Things to do in La Paz

Museums · Historic Sites · Shopping

Side Trips

Find places to stay Jul 10 — 13:

1
night
Uyuni, Bolivia

Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Kick off your visit on the 14th (Tue): head off the coast to Isla Incahuasi and then explore the striking landscape at Salar de Uyuni.

To find more things to do, traveler tips, maps, and other tourist information, you can read our Uyuni trip planner.

Getting from La Paz to Uyuni by flight takes about 3 hours. Other options: drive; or take a bus. Traveling from La Paz in July, expect nights in Uyuni to be a bit warmer, around 3°C, while days are little chillier, around 4°C. Finish your sightseeing early on the 14th (Tue) to allow enough time to travel to Gramado.

Things to do in Uyuni

Parks · Nature
Find places to stay Jul 13 — 14:

4
nights
Gramado, Brazil

Hydrangea Garden

Surrounded by impressive mountain scenery in the state of Rio Grande do Sul, the small city of Gramado charms visitors with its alpine European-style architecture and blossoming flowers.
Do some cultural sightseeing at Vinicola Salvattore and Igreja Matriz Sao Pedro Apostolo. Do your shopping at Doces Silber and Galeria Arte12b. Explore Gramado's surroundings by going to Vidraria Madelustre - Mundo do Vidro (in Garibaldi), Bento Goncalves (Vinicola Torcello, Cristofoli Vinhos de Familia, &more) and Adelmo Trott Historic Municipal Museum (in Taquara). There's much more to do: contemplate the waterfront views at Lago Negro, pause for some serene contemplation at Paroquia Nossa Senhora de Lourdes, examine the collection at Instituto Hercules Gallo, and learn about winemaking at Casa Seganfredo.

To find more things to do, maps, other places to visit, and other tourist information, you can read our Gramado online itinerary planner.

Getting from Uyuni to Gramado by flight takes about 14 hours. Other options: drive; or do a combination of train, car, bus, and taxi. Due to the time zone difference, you'll lose 1 hour traveling from Uyuni to Gramado. Finish your sightseeing early on the 19th (Sun) so you can travel to Sao Paulo.

Things to do in Gramado

Museums · Wineries · Historic Sites · Parks

Side Trips

Find places to stay Jul 15 — 19:

5
nights
Sao Paulo, Brazil

Land of Drizzle

Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
For shopping fun, head to Paulista Avenue or The Julio Prestes Cultural Center - Sala Sao Paulo. Museum-lovers will get to explore Museu de Arte de Sao Paulo Assis Chateaubriand - MASP and Museu da Lingua Portuguesa. You'll find plenty of places to visit near Sao Paulo: Aparecida (Memorial da Devocao Nossa Senhora Aparecida, National Sanctuary of Our Lady of Aparecida, &more). There's still lots to do: explore the world behind art at Pinacoteca do Estado de Sao Paulo, browse the fresh offerings at Mercado Municipal de São Paulo, stroll around Parque Ibirapuera, and examine the collection at Museu de Arte Brasileira - FAAP.

For more things to do, other places to visit, traveler tips, and more tourist information, use the Sao Paulo trip planner.

Getting from Gramado to Sao Paulo by flight takes about 4.5 hours. Other options: drive; or do a combination of taxi and bus. Expect a daytime high around 26°C in July, and nighttime lows around 15°C. Finish up your sightseeing early on the 24th (Fri) so you can travel to Rio de Janeiro.

Things to do in Sao Paulo

Museums · Shopping · Parks · Neighborhoods

Side Trip

Find places to stay Jul 19 — 24:

6
nights
Rio de Janeiro, Brazil

Marvelous City

Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Visit Copacabana Beach and Praia de Ipanema for some beach relaxation. Do some cultural sightseeing at Corcovado - Christ the Redeemer and Pedra do Arpoador. Explore Rio de Janeiro's surroundings by going to Niteroi (Fortaleza de Santa Cruz da Barra & Museu de Arte Contemporanea de Niteroi) and Petropolis (Museu de Porcelana de Petropolis, Museu Casa de Santos Dumont, &more). The adventure continues: explore the world behind art at Centro Cultural Banco do Brasil - CCBB Rio de Janeiro, explore the historical opulence of Ilha Fiscal, kick back and relax at Barra da Tijuca Beach, and take a stroll around Centro Cultural Carioca.

Discover how to plan a Rio de Janeiro trip in just a few steps with Inspirock's itinerary builder.

Fly from Sao Paulo to Rio de Janeiro in 3.5 hours. Alternatively, you can drive; or take a bus. In July, Rio de Janeiro is a bit warmer than Sao Paulo - with highs of 30°C and lows of 22°C. Finish your sightseeing early on the 30th (Thu) so you can travel back home.

Things to do in Rio de Janeiro

Museums · Parks · Historic Sites · Outdoors

Side Trips

Find places to stay Jul 24 — 30:

Ecuador travel guide

4.5
Landmarks · Sacred & Religious Sites · History Museums
With abundant opportunities to discover fascinating World Heritage Sites, a holiday in Ecuador remains among the most culturally enriching travel experiences. Home to the world's highest active volcano, this little country packs a big punch when it comes to tourist activities. Some of the most popular things to do in Ecuador include visits to its astonishingly biodiverse wilderness areas, home to some 1,500 bird species, 840 species of amphibians and reptiles, and nearly 20,000 plant species. Of course, the highlight of many Ecuador vacations is bound to be the Galapagos Islands, made famous by naturalist Charles Darwin. Aside from the stunning nature, Ecuador also boasts many historic cities filled with photogenic colonial-era churches, mansions, and plazas.

Peru travel guide

4.6
Historic Sites · Parks · Landmarks
Land of the Incas
In a country renowned for its pre-Columbian archeological sites, no Peru vacation would be complete without an adrenaline-inducing hike to Machu Picchu, World Heritage-listed symbol of the once-mighty Incan Empire. Aside from visiting these spectacular ruins set against the backdrop of photogenic mountain peaks, most holidays in Peru also include an exploration of the country's pretty cities, boasting well-preserved colonial architecture and a slew of modern buildings housing fine museums, galleries, shops, and restaurants. Ideal for active vacationers, Peru trips are also tailor-made for gourmands, as the country's eclectic cuisine blends tasty influences from Africa, Asia, and Europe.

Bolivia travel guide

4.2
Landmarks · Geologic Formations · Specialty Museums
Tibet of the Americas
If you're an adventurous tourist, consider adding a Bolivia vacation to your travel itinerary. A land of rainforests, Andean glaciers, high altitude cities, and rushing rivers, Bolivia remains one of the most remote countries in the Western Hemisphere. With 60 percent of the population made up of indigenous peoples, native cultures permeate thecountry's music, architecture, and arts, as well as local folklore and traditions. Traveling in Bolivia you can experience diverse wildlife and ecosystems, learn about the country's rich history, try out its distinctive cuisine, and practice your Spanish with the locals, known for their clean and easy-to-understand accent.

Brazil travel guide

4.4
Beaches · Landmarks · Specialty Museums
Land of Brazilwood
The largest country in South America and the biggest Portuguese-speaking nation in the world, Brazil remains best known for its soccer tradition and annual Carnaval. Most visitors on holiday in Brazil come for the country's outstanding beaches, music, wildlife, and diverse neighborhoods, each one boasting its own distinct character, atmosphere, and way of life. A tour of Brazil reveals a vast land of great natural and human diversity, from its sprawling rainforest wildernesses, to its busy urban centers. There are plenty of things to do in Brazil, from basking on its coastline to chasing the samba scene or catching a picturesque sunset from one of the country's lush mountaintops.