51 days in South America & Mexico Itinerary

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.

Explore Santiago's surroundings by going to River Rafting & Tubing (in San Jose de Maipo) and Concha y Toro (in Pirque). There's still lots to do: get great views at San Cristóbal Hill, examine the collection at La Chascona, don't miss a visit to Santa Lucia Hill, and wander the streets of Barrio Bellavista.

To plan Santiago vacation without wasting time, ask Inspirock to design an itinerary.

Melbourne, Australia to Santiago is an approximately 18-hour flight. You can also do a combination of shuttle and flight; or do a combination of train and flight. The time zone difference moving from Australian Eastern Standard Time (Victoria) to Chile Time is minus 14 hours. Cap off your sightseeing on the 29th (Wed) early enough to travel to San Pedro de Atacama.

Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.

San Pedro de Atacama is known for nature, wildlife, historic sites, nightlife, and museums. Your plan includes some of its best attractions: take in the dramatic natural features at Valle De La Luna, explore the activities along Laguna Cejar, witness a stunning natural landmark at Termas Banos de Puritama, and delve into the distant past at Pukara de Quitor.

To see ratings, more things to do, reviews, and tourist information, refer to the San Pedro de Atacama trip planner .

You can do a combination of flight and shuttle from Santiago to San Pedro de Atacama in 5 hours. Alternatively, you can drive; or take a bus. In January in San Pedro de Atacama, expect temperatures between 29°C during the day and 8°C at night. Wrap up your sightseeing on the 2nd (Sun) early enough to travel to Foz do Iguacu.

A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.

Start off your visit on the 3rd (Mon): take in the spiritual surroundings of Mosque of Omar Ibn Al-Khattab and then see human ingenuity at work at Iguazu Falls. Get ready for a full day of sightseeing on the 4th (Tue): contemplate in the serene atmosphere at Buddhist Temple, then admire the engineering at Itaipu Hydroelectric Dam, and then learn about wildlife with up-close encounters at Parque das Aves Bird Park.

For other places to visit, maps, where to stay, and more tourist information, you can read our Foz do Iguacu journey maker app .

Do a combination of shuttle and flight from San Pedro de Atacama to Foz do Iguacu in 14 hours. Alternatively, you can do a combination of bus, flight, and shuttle; or drive. The time zone changes from Chile Time to Brasilia Time, which is usually a 1 hour difference. Expect a bit warmer weather when traveling from San Pedro de Atacama in February: highs in Foz do Iguacu hover around 37°C, while lows dip to 25°C. Cap off your sightseeing on the 4th (Tue) early enough to travel to Rio de Janeiro.

Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.

Rio de Janeiro is known for beaches, nature, parks, museums, and nightlife. Your plan includes some of its best attractions: take your sightseeing to a higher altitude at Sugarloaf Mountain, stroll through Leblon Beach, kick back and relax at Barra da Tijuca Beach, and explore and take pictures at Maracanã.

To find maps, ratings, where to stay, and tourist information, read Rio de Janeiro sightseeing app .

Getting from Foz do Iguacu to Rio de Janeiro by flight takes about 2.5 hours. Other options: drive; or take a bus. Expect a daytime high around 38°C in February, and nighttime lows around 28°C. Wrap up your sightseeing on the 9th (Sun) early enough to travel to Sao Paulo.

Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.

Get out of town with these interesting Sao Paulo side-trips: Orla e Jardins da Praia de Santos (in Santos), Guaruja (Acqua Mundo & Enseada Beach) and Juquehy Beach (in Sao Sebastiao). There's still lots to do: see some colorful creatures with a scuba or snorkeling tour, make a trip to Solo Sagrado De Guarapiranga, engage your brain at Instituto de Biociências da Universidade de São Paulo, and look for gifts at Morumbi Shopping.

To see other places to visit, more things to do, photos, and more tourist information, refer to the Sao Paulo online trip maker .

You can do a combination of flight and bus from Rio de Janeiro to Sao Paulo in 1.5 hours. Other options are to fly; or drive. Prepare for a bit cooler weather when traveling from Rio de Janeiro in February: high temperatures in Sao Paulo hover around 34°C and lows are around 23°C. Finish up your sightseeing early on the 13th (Thu) so you can travel to Fernando de Noronha.

With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.

Fernando de Noronha is known for beaches, museums, wildlife, outdoors, and nature. Your plan includes some of its best attractions: enjoy the sand and surf at Baia do Sancho, stroll through Praia do Leão, get outside with Baia dos Porcos, and see the interesting displays at Projeto TAMAR Fernando de Noronha - Patrocínio PETROBRAS.

To find maps, where to stay, photos, and other tourist information, go to the Fernando de Noronha holiday planning tool .

Getting from Sao Paulo to Fernando de Noronha by flight takes about 6.5 hours. The time zone difference moving from Brasilia Time to Fernando de Noronha Time is 1 hour. Traveling from Sao Paulo in February, Fernando de Noronha is somewhat warmer at night with lows of 29°C. Finish up your sightseeing early on the 18th (Tue) so you can travel to Bogota.

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.

Go for a jaunt from Bogota to Zipaquira to see Catedral de Sal about 54 minutes away. There's much more to do: examine the collection at Gold Museum (Museo del Oro), stroll around 93 Park, take your sightseeing to a higher altitude at Mount Monserrate, and explore the world behind art at Museo Botero del Banco de la Republica.

Start your trip to Bogota by creating a personalized itinerary on Inspirock.

Traveling by flight from Fernando de Noronha to Bogota takes 11.5 hours. Alternatively, you can do a combination of flight and bus. You'll gain 3 hours traveling from Fernando de Noronha to Bogota due to the time zone difference. While traveling from Fernando de Noronha, expect slightly colder days and much colder nights in Bogota, ranging from highs of 24°C to lows of 9°C. Wrap up your sightseeing on the 22nd (Sat) to allow time to travel to Cancun.

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.

Explore the numerous day-trip ideas around Cancun: Punta Laguna Nature Reserve (in Tulum) and Playa del Carmen (Quinta Avenida, Zipline, & more). Spend the 27th (Thu) in unforgettable company with a swim-with-the-dolphins experience. There's lots more to do: buy something for everyone on your list at La Isla Shopping Village, kick back and relax at Playa Delfines, and contemplate the long history of El Rey Archaeological Zone.

For traveler tips, photos, maps, and other tourist information, you can read our Cancun tour itinerary planning tool .

Traveling by flight from Bogota to Cancun takes 5 hours. Expect a bit warmer weather when traveling from Bogota in February: highs in Cancun hover around 32°C, while lows dip to 23°C. Wrap up your sightseeing on the 27th (Thu) to allow time to travel to Machu Picchu.

A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.

On the 28th (Fri), make a trip to Plaza Manco Capac and then take in the natural beauty of Hot Springs (Aguas Calientes). On your second day here, explore the ancient world of Intipuncu and then steep yourself in history at Santuario Historico de Machu Picchu.

To find ratings, maps, and tourist information, refer to the Machu Picchu online attractions planner .

Do a combination of flight and car from Cancun to Machu Picchu in 18 hours. Cap off your sightseeing on the 29th (Sat) early enough to travel to Cusco.

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.

Venture out of the city with trips to Maras (Salinas de Maras & Moray). On the 3rd (Tue), spend a fun day on foot with Walking tours. There's still lots to do: delve into the distant past at Sacsayhuaman, get engrossed in the history at Museo Inka, steep yourself in history at Tipon, and admire the masterpieces at Museo de Arte Precolombino.

For other places to visit, more things to do, reviews, and more tourist information, go to the Cusco trip planner.

Getting from Machu Picchu to Cusco by combination of train and bus takes about 3.5 hours. Other options: take a train; or drive. In February, daily temperatures in Cusco can reach 23°C, while at night they dip to 9°C. Finish your sightseeing early on the 6th (Fri) so you can travel back home.

Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.

Kick off your visit on the 7th (Sat): take in the dramatic scenery at Cataratas del Iguazu. Here are some ideas for day two: take in the dramatic scenery at Salto Bernabe Mendez, admire the sheer force of Salto San Martin, and then head off the coast to Isla San Martin.

To see more things to do, ratings, and other tourist information, read Iguazu National Park trip builder website .

Traveling by flight from Cusco to Iguazu National Park takes 12 hours. Alternatively, you can drive; or take a bus. You'll lose 2 hours traveling from Cusco to Iguazu National Park due to the time zone difference. Traveling from Cusco in March, expect Iguazu National Park to be somewhat warmer, temps between 34°C and 22°C. Finish up your sightseeing early on the 8th (Sun) so you can travel to Buenos Aires.

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.

Start off your visit on the 9th (Mon): explore and take pictures at Estadio Alberto J. Armando (La Bombonera) and then appreciate the extensive heritage of La Boca. Keep things going the next day: see the interesting displays at Museo de la Pasion Boquense, pause for some photo ops at Monumento Al Bombero, then see the interesting displays at Fundacion Proa, then get to know the fascinating history of Calle Museo Caminito, and finally get into the urban bustle at Usina del Arte.

For maps, photos, where to stay, and other tourist information, read our Buenos Aires travel planner.

Getting from Iguazu National Park to Buenos Aires by flight takes about 3.5 hours. Other options: drive; or take a bus. When traveling from Iguazu National Park in March, plan for little chillier days in Buenos Aires, with highs around 29°C, while nights are about the same with lows around 20°C. Finish your sightseeing early on the 10th (Tue) to allow enough time to travel to Los Glaciares National Park.

A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.

Start off your visit on the 11th (Wed): take in the dramatic natural features at Glaciar Seco and then take in the dramatic natural features at Perito Moreno Glacier. Keep things going the next day: take in the dramatic natural features at Glaciar Spegazzini.

To see ratings and more tourist information, you can read our Los Glaciares National Park tour itinerary planner.

You can fly from Buenos Aires to Los Glaciares National Park in 6.5 hours. Other options are to do a combination of train and bus; or take a bus. Traveling from Buenos Aires in March, expect nights in Los Glaciares National Park to be slightly colder, around 13°C, while days are much colder, around 15°C. You'll set off for home on the 13th (Fri).