60 days in South America Itinerary

60 days in South America Itinerary

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Route & dates

1
Sao Paulo, Brazil
— 2 nights
2
Punta del Este, Uruguay
— 3 nights
3
Montevideo, Uruguay
— 6 nights
4
Colonia del Sacramento, Uruguay
— 2 nights
5
Buenos Aires, Argentina
— 6 nights
6
Rosario, Argentina
— 4 nights
7
Cordoba, Argentina
— 2 nights
8
Mendoza, Argentina
— 7 nights
9
Santiago, Chile
— 4 nights
10
La Serena, Chile
— 2 nights
11
San Pedro de Atacama, Chile
— 4 nights
12
Uyuni, Bolivia
— 5 nights
13
La Paz, Bolivia
— 3 nights
14
Puno, Peru
— 3 nights
15
Arequipa, Peru
— 1 night

2
nights
Sao Paulo, Brazil

Sao Paulo
Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
To see ratings, reviews, maps, and tourist information, read Sao Paulo holiday maker site.

If you are flying in from Brazil, the closest major aiports are Congonhas Airport, Guarulhos - Governador André Franco Montoro International Airport and Viracopos International Airport. In August in Sao Paulo, expect temperatures between 28°C during the day and 15°C at night. On the 3rd (Tue), you're off to Punta del Este.

Things to do in Sao Paulo

Nightlife · Parks · Shopping
Find places to stay Aug 1 — 3:

3
nights
Punta del Este, Uruguay

Punta del Este ©
With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
You've added Museo – Taller de Casapueblo, Playa de Los Ingleses, Playa Brava, and other attractions to your itinerary.

You can plan Punta del Este trip in no time by asking Inspirock to help create your itinerary.

Getting from Sao Paulo to Punta del Este by flight takes about 6.5 hours. Other options: drive; or take a bus. Traveling from Sao Paulo in August, things will get a bit cooler in Punta del Este: highs are around 19°C and lows about 12°C. Wrap up your sightseeing by early afternoon on the 7th (Sat) to allow time for the car ride to Montevideo.

Things to do in Punta del Este

Outdoors · Beaches · Parks

Side Trips

Museo – Taller de Casapueblo, La Pedrera
Find places to stay Aug 4 — 7:
Highlights from your plan
La Pedrera ©
La Pedrera
Museo – Taller de Casapueblo ©
Museo – Taller de Casapueblo
Playa Brava ©
Playa Brava

6
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Your list of things to see and do now includes Ciudad Vieja, Escaramuza Libros, Mercado del Puerto, and other attractions. Museum-lovers will appreciate Museo del Azulejo and Museo Figari. Get some historical perspective at Parroquia Sagrado Corazon and Parroquia Tierra Santa. And it doesn't end there: get a sense of history and politics at Palacio Legislativo, look and learn at Planetario de Montevideo, don't miss a visit to Mercado Agricola Montevideo - MAM, and get a new perspective on nature at Museo Zoologico Damaso Antonio Larranaga.

To see photos and other tourist information, read Montevideo trip maker site.

Getting from Punta del Este to Montevideo by car takes about 2 hours. Other options: take a bus. Traveling from Punta del Este in August, expect little chillier with lows of 9°C in Montevideo. Finish up your sightseeing early on the 13th (Fri) so you can go by car to Colonia del Sacramento.

Things to do in Montevideo

Museums · Shopping · Neighborhoods
Find places to stay Aug 7 — 13:
Highlights from your plan
Museo del Cannabis de Montevideo ©
Museo del Cannabis de Montevideo
Pocitos ©
Pocitos
Ciudad Vieja ©
Ciudad Vieja

2
nights
Colonia del Sacramento, Uruguay

Colonia del Sacramento
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
For other places to visit, more things to do, ratings, and more tourist information, read Colonia del Sacramento road trip planning tool.

Traveling by car from Montevideo to Colonia del Sacramento takes 3 hours. Alternatively, you can take a bus. In August, plan for daily highs up to 20°C, and evening lows to 11°C. You will leave for Buenos Aires on the 15th (Sun).

Things to do in Colonia del Sacramento

Outdoors · Parks · Museums
Find places to stay Aug 13 — 15:

6
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for historic sites, nightlife, and parks. Your plan includes some of its best attractions: get to know the fascinating history of Calle Defensa.

To see maps, where to stay, more things to do, and other tourist information, you can read our Buenos Aires online travel planner.

You can ride a ferry from Colonia del Sacramento to Buenos Aires in 2 hours. In August in Buenos Aires, expect temperatures between 20°C during the day and 12°C at night. On the 21st (Sat), you're off to Rosario.

Things to do in Buenos Aires

Neighborhoods · Historic Sites
Find places to stay Aug 15 — 21:
Highlights from your plan
Calle Defensa ©
Calle Defensa

4
nights
Rosario, Argentina

Rosario ©
Once upon a time, Rosario was famous for being the birthplace of not only revolutionary leader Che Guevara, but also the Argentine flag.
Satisfy your inner culture vulture at Museo Historico del Convento San Carlos and Museo Municipal De Bellas Artes Juan B. Castagnino. You'll explore and learn at Museo de los Ninos and Museo de Arte Decorativo Firma y Odilo Estevez. The adventure continues: kick back and relax at La Florida, make a trip to Teatro El Circulo, walk around Parque de Espana, and take in the spiritual surroundings of Parroquia MarIa Auxiliadora.

To see more things to do, other places to visit, traveler tips, and other tourist information, use the Rosario trip itinerary tool.

You can drive from Buenos Aires to Rosario in 3 hours. Other options are to fly; or take a bus. Traveling from Buenos Aires in August, expect little chillier with lows of 7°C in Rosario. Cap off your sightseeing on the 25th (Wed) early enough to go by car to Cordoba.

Things to do in Rosario

Museums · Parks · Outdoors

Side Trip

Museo Historico del Convento San Carlos
Find places to stay Aug 21 — 25:
Highlights from your plan
Museo Historico del Convento San Carlos ©
Museo Historico del Convento San Carlos
Museo de Arte Decorativo Firma y Odilo Estevez ©

2
nights
Cordoba, Argentina

Cordoba ©
History lives on in the streets of Cordoba, Argentina's second-largest city.
On the 26th (Thu), examine the collection at Colegio Nacional de Monserrat, then steep yourself in history at Museo Historico UNC Manzana Jesuitica, then take in the architecture and atmosphere at Iglesia de Los Capuchinos, and finally contemplate the long history of Paseo del Buen Pastor. Get ready for a full day of sightseeing on the 27th (Fri): see the interesting displays at Museo Palacio Ferreyra, get engrossed in the history at Museo Historico Provincial Marques de Sobre Monte, then pause for some serene contemplation at Monasterio de Santa Teresa, and finally take in the spiritual surroundings of Iglesia Catedral de Córdoba.

For more things to do, ratings, and tourist information, go to the Cordoba trip planner.

Traveling by car from Rosario to Cordoba takes 4 hours. Alternatively, you can take a bus; or fly. Expect slightly colder weather when traveling from Rosario in August: highs in Cordoba hover around 18°C, while lows dip to 18°C. Finish your sightseeing early on the 27th (Fri) to allow enough time to travel to Mendoza.

Things to do in Cordoba

Historic Sites · Museums
Find places to stay Aug 25 — 27:
Highlights from your plan
Museo Historico UNC  Manzana Jesuitica ©
Museo Historico UNC Manzana Jesuitica
Paseo del Buen Pastor ©
Paseo del Buen Pastor

7
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Museum-lovers will get to explore Museo Fundacional and Museo Nacional Del Vino y la Vendimia. Santuario Virgen de Lourdes and Santuario de Maria Auxiliadora will appeal to history buffs. Get out of town with these interesting Mendoza side-trips: Huayra Paseos en Velero (in Potrerillos), Monasterio del Cristo Orante (in Tupungato) and Bodegas Salentein (in Los Arboles). Dedicate the 28th (Sat) to wine at some of the top wineries in the area. There's still lots to do: learn about winemaking at Bodega La Azul, identify plant and animal life at Reserva Natural Villavicencio, take in the exciting artwork at Finca Agostino, and stroll around Parque General San Martin.

To find other places to visit, photos, more things to do, and other tourist information, use the Mendoza holiday builder tool.

You can fly from Cordoba to Mendoza in 4 hours. Other options are to drive; or take a bus. While traveling from Cordoba, expect a bit warmer days and little chillier nights in Mendoza, ranging from highs of 22°C to lows of 5°C. Finish your sightseeing early on the 4th (Sat) to allow enough time to travel to Santiago.

Things to do in Mendoza

Wineries · Historic Sites · Tours

Side Trips

Maipu, Bodega La Rural, Santuario Virgen de Lourdes, Huayra Paseos en Velero, Reserva Natural Villavicencio
Find places to stay Aug 28 — Sep 4:
Highlights from your plan
Bodega Tierras Altas ©
Bodega Tierras Altas
Wine Tours & Tastings
Bodega Roberto Bonfanti ©
Bodega Roberto Bonfanti

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get a sense of the local culture at La Chascona and Concha y Toro. Appreciate the collections at Museo Chileno de Arte Precolombino and Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania. There's still lots to do: stroll around Cerro Santa Lucia, enjoy breathtaking views from Sky Costanera, take in the pleasant sights at Plaza de Armas, and surround yourself with nature on Horse Riding Chile.

For traveler tips, where to stay, more things to do, and tourist information, read our Santiago attractions planner.

You can fly from Mendoza to Santiago in 4.5 hours. Alternatively, you can drive; or take a bus. Due to the time zone difference, you'll gain 1 hour traveling from Mendoza to Santiago. Wrap up your sightseeing on the 8th (Wed) early enough to travel to La Serena.

Things to do in Santiago

Parks · Museums · Outdoors

Side Trip

Concha y Toro
Find places to stay Sep 4 — 8:
Highlights from your plan
Horse Riding Chile ©
Horse Riding Chile
La Chascona ©
La Chascona
Museo Chileno de Arte Precolombino ©
Museo Chileno de Arte Precolombino

2
nights
La Serena, Chile

La Serena ©
Packed with old stone churches in a unique urban landscape, La Serena represents one of Chile's oldest settlements, equally popular with architecture buffs and beachgoers.
Kick off your visit on the 9th (Thu): visit a coastal fixture at Faro Punta Tortuga, pause for some photo ops at Cruz Del Tercer Milenio, and then look for all kinds of wild species at Central Tour la Serena. Here are some ideas for day two: get engrossed in the history at Archaeological Museum, then enjoy the sand and surf at Avenida del Mar, and then visit a coastal fixture at Faro Monumental de La Serena.

To find reviews, more things to do, maps, and other tourist information, read our La Serena trip itinerary planner.

You can fly from Santiago to La Serena in 3.5 hours. Other options are to drive; or take a bus. In September, plan for daily highs up to 19°C, and evening lows to 10°C. Cap off your sightseeing on the 10th (Fri) early enough to travel to San Pedro de Atacama.

Things to do in La Serena

Outdoors · Historic Sites · Wildlife

Side Trip

Coquimbo
Find places to stay Sep 8 — 10:
Highlights from your plan
Central Tour la Serena ©
Central Tour la Serena
Archaeological Museum ©
Archaeological Museum
Faro Punta  Tortuga ©
Faro Punta Tortuga

4
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
You'll explore and learn at Father Le Paige Museum and Observatorio Etno-Astronomico Licanantay. Get some cultural insight at Pukara de Quitor and San Pedro de Atacama Celestial Explorations. Go for a jaunt from San Pedro de Atacama to Toconao to see Cementerio de Toconao about 38 minutes away. Next up on the itinerary: get outside with On Safari Atacama, examine the collection at Museo del Meteorito, explore the striking landscape at Valle De La Luna, and pause for some serene contemplation at Iglesia de San Pedro de Atacama.

To find traveler tips and other tourist information, you can read our San Pedro de Atacama trip builder website.

Getting from La Serena to San Pedro de Atacama by flight takes about 4.5 hours. Other options: drive; or take a bus. Traveling from La Serena in September, expect nights in San Pedro de Atacama to be slightly colder, around 2°C, while days are somewhat warmer, around 27°C. Finish your sightseeing early on the 15th (Wed) so you can travel to Uyuni.

Things to do in San Pedro de Atacama

Museums · Parks · Wildlife

Side Trip

Cementerio de Toconao
Find places to stay Sep 11 — 15:
Highlights from your plan
On Safari Atacama ©
On Safari Atacama
Salar de Tara ©
Salar de Tara
Pukara de Quitor ©
Pukara de Quitor

5
nights
Uyuni, Bolivia

Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Appreciate the collections at Train Cemetery and Museo de la Llama y la Sal. Spend the 18th (Sat) wandering through the wild on a nature and wildlife tour. There's still lots to do: explore the striking landscape at Salar de Uyuni, don't miss a visit to Plaza Arce, see Off-Road Tours, and head off the coast to Isla Incahuasi.

For traveler tips, maps, where to stay, and tourist information, you can read our Uyuni tour itinerary planning app.

You can do a combination of bus and taxi from San Pedro de Atacama to Uyuni in 11.5 hours. Other options are to drive; or do a combination of bus and taxi. When traveling from San Pedro de Atacama in September, plan for much colder days in Uyuni, with highs around 1°C, while nights are about the same with lows around 0°C. On the 21st (Tue), you're off to La Paz.

Things to do in Uyuni

Outdoors · Tours · Nature

Side Trip

Museo de la Llama y la Sal
Find places to stay Sep 15 — 21:
Highlights from your plan
Nature & Wildlife Tours
Train Cemetery ©
Train Cemetery
Iglesia San Cristobal Lipez ©
Iglesia San Cristobal Lipez

3
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
Do some cultural sightseeing at Tiwanaku and Museo de Metales Preciosos. You'll explore and learn at Museo de Textiles Andinos Bolivianos and National Museum of Ethnography and Folklore. Step out of La Paz to go to Tiahuanaco and see Puma Punku, which is approximately 1h 10 min away. There's still lots to do: don't miss a visit to Mercado de Las Brujas, admire the striking features of Iglesia de San Francisco, get a sense of history and politics at Centro de Informacion Turistica, and let the river carry you with a rafting and tubing tour.

For where to stay, reviews, ratings, and more tourist information, read La Paz online trip maker.

Getting from Uyuni to La Paz by flight takes about 4 hours. Other options: drive; or do a combination of taxi and bus. When traveling from Uyuni in September, plan for much warmer days and about the same nights in La Paz: temperatures range from 18°C by day to 0°C at night. Finish your sightseeing early on the 25th (Sat) to allow enough time to drive to Puno.

Things to do in La Paz

Historic Sites · Museums · Outdoors

Side Trip

Puma Punku
Find places to stay Sep 21 — 25:
Highlights from your plan
Tiwanaku ©
Tiwanaku
Puma Punku ©
Puma Punku
Museo de Textiles Andinos Bolivianos ©
Museo de Textiles Andinos Bolivianos

3
nights
Puno, Peru

Puno ©
Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Start off your visit on the 26th (Sun): step off the mainland to explore Taquile Island and then stroll the grounds of Sillustani. Here are some ideas for day two: slough off your stress at Inca Sauna, then get a dose of the wild on Suri Explorer, and then step off the mainland to explore Uros Floating Islands.

Discover how to plan a Puno trip in just a few steps with Inspirock's itinerary builder.

Traveling by car from La Paz to Puno takes 4 hours. Alternatively, you can take a bus. The time zone changes from Bolivia Time to Peru Standard Time, which is usually a -1 hour difference. While traveling from La Paz, expect somewhat warmer days and about the same nights in Puno, ranging from highs of 22°C to lows of 0°C. Finish your sightseeing early on the 28th (Tue) to allow enough time to drive to Arequipa.

Things to do in Puno

Nature · Parks · Outdoors
Find places to stay Sep 25 — 28:
Highlights from your plan
Taquile Island ©
Taquile Island
Suri Explorer ©
Suri Explorer
Inca Sauna ©
Inca Sauna

1
night
Arequipa, Peru

Arequipa ©
In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Kick off your visit on the 28th (Tue): steep yourself in history at Historic Centre of Arequipa, then see the interesting displays at Santa Catalina Monastery, and then explore the galleries of Arte Colonial.

To see traveler tips, reviews, more things to do, and more tourist information, refer to the Arequipa trip planning app.

Traveling by car from Puno to Arequipa takes 4.5 hours. Alternatively, you can take a bus. Traveling from Puno in September, Arequipa is somewhat warmer at night with lows of 11°C. Finish up your sightseeing early on the 29th (Wed) so you can travel back home.

Things to do in Arequipa

Museums · Historic Sites · Neighborhoods
Find places to stay Sep 28 — 29:
Highlights from your plan
Santa Catalina Monastery ©
Santa Catalina Monastery
Museo Santuarios Andinos ©
Museo Santuarios Andinos
Historic Centre of Arequipa ©
Historic Centre of Arequipa

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